Systematic reviews of diagnostic test accuracy studies: Introduction to meta-analysis
Leeberk Raja Inbaraj, ICMR- National Institute for Research in Tuberculosis
Ridhi Agarwal, University of Birmingham
Sarah Berhane, University of Birmingham
Background: For making informed decisions about medical tests, healthcare organisations and policymakers typically rely on information from studies that assess diagnostic accuracy, i.e., how well a test gets the diagnosis right in people who have and those who do not have the target condition. Therefore, it is essential that valid methods are used to produce high quality evidence reviews that will be used to inform recommendations for patient care. This core workshop organised by the Cochrane Screening and Diagnostic Tests Methods Group is designed for those who have a keen interest in gaining insight into test accuracy meta-analysis and how to use Review Manager (RevMan) to produce graphical summaries.
Objectives: To introduce the concepts underlying test accuracy meta-analysis and recommended statistical methods, and to demonstrate graphical capabilities within RevMan.
Description: Using published examples, participants will learn of key challenges, best practice for conducting test accuracy meta-analysis and how to present results. Specifically, the workshop is based on the guidelines formulated in the new Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy. The workshop will be delivered through an interactive presentation, discussions and practical demonstrations using RevMan Web. Participants are expected to bring a laptop. Those who do not have a laptop will still benefit from the onscreen demo and discussions. Prior to the workshop, participants will be sent the RevMan file that will be used during the workshop.