GRADE target of certainty rating and implications for judgements regarding imprecision
Gordon Guyatt, McMaster University
Objectives: This workshop will introduce participants to the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) guidance on choosing targets of certainty of evidence and its implication on rating imprecision of evidence.
Description: We will give a presentation to start the workshop, providing an overview of some basic concepts regarding GRADE certainty of evidence (target of certainty of evidence, possible thresholds/ranges of interest), practical principles on how to determine targets of certainty ratings, and GRADE updated guidance on imprecision ratings (primary approach for imprecision ratings in both systematic reviews and guidelines, situations in which one should consider rating done more than one levels for imprecision). Next, participants will receive examples from existing reviews. We will facilitate participants to discuss in these examples their judgements regarding the target of certainty ratings and how many level(s) to rate down for imprecision. After discussions, we will provide tips for each example. At the end, we will encourage participants to share their perspectives and opinions on the updated GRADE guidance presented.